Cannabinoids Offer Novel Option For Brain Cancer Treatment, Study Says - Jan 24, 2008

Cannabinoids possess anti-tumor activity in glioblastoma cell lines and may offer a new therapeutic option for the treatment of brain cancer, according to a review published in the January issue of the journal Expert Review of Neurotherapeutics.

Investigators at the University of Insurbia, Center of Neurosciene, wrote: "[C]annabinoids have been shown to exert antiproliferative effects on a wide spectrum of cells in culture. Of interest, cannabinoids have displayed a great potency in reducing glioma tumor growth either in vitro or in animal experimental models. … Moreover, cannabinoids appear to be selective antitumoral agents as they kill glioma cells without affecting the viability of nontransformed counterparts."

In 2006, investigators at Complutense University in Spain reported that the intracranial administration of THC decreased recurrent GBM tumor growth in humans.

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