Cannabinoids Offer “Attractive Target” For Cancer Therapy, Study Says

Cannabinoids selectively target cancer cells and inhibit tumor growth, according to a forthcoming review to be published in the journal Seminars in Cancer Biology.

Investigators at the Karolinska Institute in Stockholm reported, "[C]annabinoids may have … inhibitory effects on tumor growth, angiogenesis (the formation of new blood vessels), migration and metastasis (the transfer of malignant cells from one site to another). Remarkably, these effects may be selective for the cancer cells, while normal cells and tissues are spared."

Authors concluded, "Such apparent tumor cell selectivity makes the endocannabinoid system an attractive potential target for cancer therapy."

Last month, investigators at the University of Wisconsin School of Medicine and Public Health reported in the journal Cancer Research that the administration of cannabinoids halts the spread of a wide range of cancers, including brain cancer, prostate cancer, breast cancer, lung cancer, skin cancer, pancreatic cancer, and lymphoma.

In November, researchers at the California Pacific Medical Center Research Institute reported that the administration of the non-psychoactive cannabinoid cannabidiol limits the activity of the breast cancer metastasis gene Id-1, stating, "[Cannabidiol] offers hope of a non-toxic therapy that could [treat aggressive forms of cancer] without any of the painful side effects [of chemotherapy.]"

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